Defenders Gary Cahill and David Luiz and midfielders N’Golo Kante and Eden Hazard are Chelsea’s representatives.
Tottenham’s quartet are defenders Kyle Walker and Danny Rose, midfielder Dele Alli and forward Harry Kane.
Manchester United goalkeeper David de Gea, Liverpool’s Sadio Mane and Everton forward Romelu Lukaku are also picked.
The divisional teams of the year have also been announced ahead of the 44th PFA Awards, which are being held in London on Sunday, 23 April.
The PFA Players’ Player of the Year and PFA Young Player of the Year will also be revealed at the event.
The votes were provided by PFA members from 100 clubs from the Premier League, Football League and Women’s Super League.
Four from Brighton in championship team
Four players from recently promoted Brighton feature in the Championship team of the year – Goalkeeper David Stockdale, defenders Bruno and Lewis Dunk and the division’s player of the year, midfielder Anthony Knockaert.
Newcastle provide three players in defender Jamaal Lascelles, midfielder Jonjo Shelvey and forward Dwight Gayle. Chris Wood of Leeds, the top-scorer with 25 league goals, is also selected.
Fulham have two players in the team – defender Ryan Sessegnon and Tom Cairney, who is named in midfield along with Huddersfield’s Aaron Mooy.
PFA teams of the year
Premier League: David de Gea (Manchester United); Kyle Walker (Tottenham), David Luiz (Chelsea), Gary Cahill (Chelsea), Danny Rose (Tottenham); Dele Alli (Tottenham), Eden Hazard (Chelsea), N’Golo Kanté (Chelsea), Sadio Mané (Liverpool); Harry Kane (Tottenham), Romelu Lukaku (Everton).
Championship: David Stockdale (Brighton); Bruno Saltor (Brighton), Lewis Dunk (Brighton), Jamaal Lascelles (Newcastle), Ryan Sessegnon (Fulham); Tom Cairney (Fulham), Anthony Knockaert (Brighton), Aaron Mooy (Huddersfield), Jonjo Shelvey (Newcastle); Dwight Gayle (Newcastle), Chris Wood (Leeds).
League One: Simon Moore (Sheffield United); Kieron Freeman (Sheffield United), Mark Beevers (Bolton), David Wheater (Bolton), James Meredith (Bradford); Mark Duffy (Sheffield United), John Fleck (Sheffield United), Josh Morris (Scunthorpe), Erhun Oztumer (Walsall); Billy Sharp (Sheffield United), James Vaughan (Bury).
League Two: Luke McCormick (Plymouth); Kelvin Mellor (Blackpool), Sonny Bradley (Plymouth), Christian Burgess (Portsmouth), Enda Stevens (Portsmouth); Nicky Adams (Carlisle), Luke Berry (Cambridge), James Coppinger (Doncaster), Graham Carey (Plymouth); Danny Hylton (Luton), John Marquis (Doncaster).
Women’s Super League: Mary Earps (Reading); Lucy Bronze (Manchester City), Jennifer Beattie (Manchester City), Steph Houghton (Manchester City), Jess Carter (Birmingham City); Karen Carney (Chelsea), Jill Scott (Manchester City), Jordan Nobbs (Arsenal), Caroline Weir (Liverpool); Jane Ross (Manchester City), Eniola Aluko (Chelsea Ladies).
